HMM-161 deployed May 1965 to Hue/Phu Bai, Republic of Vietnam and attached to MAG 16, 1st MAW. They then relocated Jan. 1966 to Futema, Okinawa and redeployed April 1966 to Da Nang, Republic of Vietnam. Once again they redeployed June 1966 to Phu Bai, Republic of Vietnam and relocated Nov. 1966 to Futema, Okinawa. The squadron attached to MAG 15, 9th Marine Amphibious Brigade.They relocated during Dec. 1996 to MCAS New River, N.C. and attached to MAG 26, 2d MAW. HMM-161 then redeployed May 1968 to Quang Tri, Republic of Vietnam and attached to provisional MAG 39, 1st MAW when they redeployed Oct. 1969 to Phu Bai, Republic of Vietnam, and attached to MAG 16, 1st MAW.